V.iii.7.3.c.Rating Prostate Cancer
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The table below describes common treatments for prostate cancer as well as the side effects and rating considerations associated with the treatment.
Type of Treatment |
Potential Side Effects |
Rating Considerations |
Watchful waiting
- also called
- conservative management
- observation, or
- surveillance, and
- no immediate specific therapy is being used, but cancer is active.
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- None, except for the continued presence and potential metastasis of cancer
- often used when life expectancy is short due to age or other illness since prostate cancer is slow- growing.
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- Review to confirm the continuation of active cancer previously confirmed by biopsy.
- Evaluate at 100 percent, despite the lack of treatment and possible lack of symptoms.
Note: If watchful waiting is used to closely monitor inactive cancer that is in remission, evaluate based on residuals since the cancer is no longer active. |
Radical prostatectomy surgery which
- is characterized by removal of the prostate gland and seminal vesicles
- is the most common treatment for localized cancer
- can be curative, and
- may involve a nerve-sparing procedure to improve chances that the patient will retain normal erectile function.
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- Impotence, and/or
- incontinence.
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- In all cases of radical prostatectomy, award SMC (k) for loss of use (LOU) of a creative organ.
- Consider service connection (SC) for ED on a facts-found basis.
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Cryotherapy, also known as cryosurgery or cryoablation, is a procedure by which the prostate and nearby tissues are frozen with liquid nitrogen via probes in the perineum. |
- Impotence
- incontinence
- urethral scarring, and
- rectourethral fistula (rare).
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Consider SMC (k) on a facts-found basis. |
Radiation
- can be curative if cancer is confined to the prostate and surrounding tissues and PSA is 15 nanograms (ng)/ml or less
- is also used as palliative therapy to relieve symptoms of advanced cancer, such as bone pain due to metastasis, and
- can be
- internal radiation therapy, or brachytherapy, in which radioactive seeds are implanted in the prostate, including
- high dose radiation (HDR) in which seeds are implanted for less than a day and then removed, and radiation is present only while seeds are in place, or
- low dose radiation (LDR) in which seeds are permanently implanted and give off radiation for weeks to months, depending on the radioisotope used, or
- external radiation therapy, in which radiation is delivered by high-energy eternal radiation for six to eight weeks.
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- After external beam radiation
- impotence, and/or
- incontinence, and
- after brachytherapy
- impotence
- incontinence
- bowel problems, and/or
- urethral complications.
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- After internal HDR
- the radiation continues only for hours or days, so a six-month assignment of temporary 100-percent under 38 CFR 4.115b, DC 7528 is appropriate, and
- consider SMC (k) for impotence on a facts-found basis.
- After internal LDR
- the effective radiation should be gone by one year
- assign a 100-percent evaluation for one year, and
- schedule a review exam six months following the cessation of the one-year treatment period.
Note: If radiation is used only as palliative therapy in advanced cancer, the 100-percent evaluation will continue because the cancer will remain active. Therefore
- review for metastatic disease, and
- consider permanency.
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Hormone therapy is primarily for palliation of prostate cancer which is not confined to the prostate for the purpose of testosterone deprivation.
Types of hormone therapy include
- orchiectomy, the removal of testes to prevent testosterone production
- luteinizing hormone releasing hormone agonists (LHRH analogs), which can lower the testosterone as effectively as orchiectomy such as
- Lupron (leuprolide)
- Zoladex (goserelin), and
- busrelin
- estrogens or estrogen-like drugs, which lower the level of testosterone
- second-line hormonal drugs, which are used when first-line hormone therapy fails
- anti-androgens, which block the ability of the body to use androgens, such as
- Eulexin (flutamide)
- Casodex (bicalutamide), and
- Nilandron (nilutamide), and
- combined hormone therapy, which is an anti-androgen combined with orchiectomy or an LHRH agonist (analog).
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- After any hormone therapy
- hot flashes
- osteoporosis
- loss of muscle mass
- after orchiectomy
- impotence
- sterility
- loss of sex drive
- after anti-androgen therapy
- gastrointestinal upset
- breast tenderness
- gynecomastia
- decreased libido
- impotence
- hot flashes, and
- after LHRH analogs
- impotence
- hot flashes, and
- gynecomastia.
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- Orchiectomy results in anatomical loss of a creative organ; therefore
- Hormone therapy may continue for many years; therefore
- review treatment records for expected duration of treatment, and
- consider permanence.
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Chemotherapy |
Depending on the type of chemotherapy used, there are multiple possible side effects. |
Chemotherapy is used for palliation as current agents will not eradicate prostate cancer; therefore
- evaluate as 100 percent
- consider permanence
- review for metastatic disease, and
- if metastatic disease affects body systems other than the genitourinary system, award a separate evaluation for confirmed metastatic disease under the appropriate code for that body system.
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References: For more information on
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