Note (a): Systemic therapy is treatment administered through any route other than the skin; topical therapy is treatment administered through the skin.
Note (b): Two or more skin conditions may be combined under § 4.25 only if separate skin areas are involved. If the same area is involved, only the highest evaluation applies.
| Description | Rating |
|---|---|
| 7817 Erythroderma: | |
| Generalized involvement of the skin with systemic manifestations (such as fever, weight loss, or hypoproteinemia) AND one of the following | 100 |
| Constant or near-constant systemic therapy such as therapeutic doses of corticosteroids, other immunosuppressive drugs, retinoids, PUVA (psoralen with long-wave ultraviolet-A light), UVB (ultraviolet-B light) treatments, biologics, or electron beam therapy required over the past 12 month period; or | |
| No current treatment due to a documented history of treatment failure with 2 or more treatment regimens | 100 |
| Generalized involvement of the skin without systemic manifestations and one of the following | |
| Constant or near-constant systemic therapy such as therapeutic doses of corticosteroids, other immunosuppressive drugs, retinoids, PUVA, UVB treatments, biologics, or electron beam therapy required over the past 12-month period; or | |
| No current treatment due to a documented history of treatment failure with 1 treatment regimen | 60 |
| Any extent of involvement of the skin, and any of the following therapies required for a total duration of 6 weeks or more, but not constantly, over the past 12-month period: systemic therapy such as therapeutic doses of corticosteroids, other immunosuppressive drugs, retinoids, PUVA, UVB treatments, biologics, or electron beam therapy | 30 |
| Any extent of involvement of the skin, and any of the following therapies required for a total duration of less than 6 weeks over the past 12-month period: systemic therapy such as therapeutic doses of corticosteroids, other immunosuppressive drugs, retinoids, PUVA, UVB treatments, biologics, or electron beam therapy | 10 |
| Any extent of involvement of the skin, and no more than topical therapy required over the past 12-month period | 0 |
| Note: Treatment failure is defined as either disease progression, or less than a 25 percent reduction in the extent and severity of disease after four weeks of prescribed therapy, as documented by medical records |